Part 13 Cosmetic Manufacturing Part 13.1 Cosmetic Manufacturing Processes Editor: Bruce Victor Contributors: Donald S. Buell Este Lauder Companies, Inc. Rose Khosravani Este Lauder Companies, Inc. Doug J. Melenkevitz Este Lauder Companies, Inc. Bruce L. Victor Este Lauder Companies, Inc. David P. Yacko Este Lauder Companies, Inc. Meyer R. Rosen Interactive Consulting, Inc. Table of Contents: 13.1 Introduction 13.1.2 Unit Operations a. Mixing 1. Quality of Mixing 2. Mixing Rheology 3. Heat Transfer 4. Types of Reactors and Their Use in Cosmetics 5. Emulsion Processing EquipmentHeat Transfer 13.1.3.1 Wet SystemsSingle Phase (Miscible) Systems a. Flow Patterns: Fluids with Low or Medium Viscosity (< 5,000 centipoise) b. Impellers for Liquids of Low and Medium Viscosity c. Power Consumption d. Pumping Capacity and Velocity Head e. Mixing Time f. Influence of Vessel Shape g. Flow Patterns: Fluids of High Viscosity h. Impeller Types and Mixers for High-Viscosity Fluids 13.1.3.2 Wet Systems - Multiphase Systems a. The Emulsification Process b. Orientation of Phases c. Addition of Surfactant d. Emulsion Temperature e. Emulsion Processing Equipment - Mixing f. High-Shear Mixers and Dispersion Equipment g. Batch Homogenizers h. Continuous High-Pressure Homogenizers and Mixers i. Processing of Water in Silicone Emulsions j. Liposome Production 13.1.3.3 Wet SystemsLiquidSolid Systems a. Suspension of Solids b. Milling Equipment c. Colloid Mills d. Ball Mills e. Three-Roll Mills 13.1.4 Filling a. Filling Parameters b. Filling Machines c. Filling Low-Viscosity Products (Lotions, Toners, Liquid Makeups) d. Filling High-Viscosity Products (Creams, Mascaras, Masks) e. FillingTraditional Lotion Products f. Filling Shear-Sensitive Products g. Filling Shampoos, Conditioners, CleansersProducts That Aerate h. Packaging Lines i. Warm and Hot FillsCreams and Dispersions j. Warm and Hot FillsGodet Products k. Warm and Hot FillsLipsticks, Lip Balms, Suppositories l. Antiperspirants and Deodorants 13.1.5 Scale-Up a. Agitation